unclassified Lachnoclostridium


Species:unclassified Lachnoclostridium


Gut outflow:0.667
Disease Association:

Colon adenoma (ES=0.304436)

Colorectal cancer (ES=1)

Colorectal cancer (ES=0.408457)

Colorectal cancer (ES=0.357291)

Healthy (ES=0.31459)

Renal cancer (ES=0.329064)

Type 1 diabetes (ES=0.643097)

Region Enrichment:Spain


Abundance overview



Without outliers
log Abundance



Without outliers
log Abundance

Function overview

KEGG pathways

In the linked pathways:
red=enriched, blue=depleted

ko00010 - Glycolysis / Gluconeogenesis

ko00020 - Citrate cycle (TCA cycle)

ko00030 - Pentose phosphate pathway

ko00040 - Pentose and glucuronate interconversions

ko00051 - Fructose and mannose metabolism

ko00052 - Galactose metabolism

ko00053 - Ascorbate and aldarate metabolism

ko00061 - Fatty acid biosynthesis

ko00072 - Synthesis and degradation of ketone bodies

ko00230 - Purine metabolism

ko00240 - Pyrimidine metabolism

ko00250 - Alanine, aspartate and glutamate metabolism

ko00260 - Glycine, serine and threonine metabolism

ko00270 - Cysteine and methionine metabolism

ko00290 - Valine, leucine and isoleucine biosynthesis

ko00300 - Lysine biosynthesis

ko00340 - Histidine metabolism

ko00400 - Phenylalanine, tyrosine and tryptophan biosynthesis

ko00450 - Selenocompound metabolism

ko00460 - Cyanoamino acid metabolism

ko00471 - D-Glutamine and D-glutamate metabolism

ko00472 - D-Arginine and D-ornithine metabolism

ko00473 - D-Alanine metabolism

ko00500 - Starch and sucrose metabolism

ko00511 - Other glycan degradation

ko00520 - Amino sugar and nucleotide sugar metabolism

ko00521 - Streptomycin biosynthesis

ko00550 - Peptidoglycan biosynthesis

ko00561 - Glycerolipid metabolism

ko00620 - Pyruvate metabolism

ko00630 - Glyoxylate and dicarboxylate metabolism

ko00633 - Nitrotoluene degradation

ko00640 - Propanoate metabolism

ko00650 - Butanoate metabolism

ko00660 - C5-Branched dibasic acid metabolism

ko00670 - One carbon pool by folate

ko00710 - Carbon fixation in photosynthetic organisms

ko00720 - Carbon fixation pathways in prokaryotes

ko00730 - Thiamine metabolism

ko00740 - Riboflavin metabolism

ko00750 - Vitamin B6 metabolism

ko00760 - Nicotinate and nicotinamide metabolism

ko00770 - Pantothenate and CoA biosynthesis

ko00780 - Biotin metabolism

ko00785 - Lipoic acid metabolism

ko00903 - Limonene and pinene degradation

ko00910 - Nitrogen metabolism

ko00970 - Aminoacyl-tRNA biosynthesis

ko00983 - Drug metabolism - other enzymes

ko02030 - Bacterial chemotaxis

ko02040 - Flagellar assembly

ko02060 - Phosphotransferase system (PTS)

ko03030 - DNA replication

ko03410 - Base excision repair

ko03430 - Mismatch repair

ko03440 - Homologous recombination

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KEGG modules

M00002 - Glycolysis, core module involving three-carbon compounds

M00003 - Gluconeogenesis, oxaloacetate => fructose-6P

M00004 - Pentose phosphate pathway (Pentose phosphate cycle)

M00005 - PRPP biosynthesis, ribose 5P => PRPP

M00006 - Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P

M00007 - Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P

M00008 - Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate

M00010 - Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate

M00015 - Proline biosynthesis, glutamate => proline

M00016 - Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine

M00019 - Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine

M00020 - Serine biosynthesis, glycerate-3P => serine

M00021 - Cysteine biosynthesis, serine => cysteine

M00022 - Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate

M00023 - Tryptophan biosynthesis, chorismate => tryptophan

M00026 - Histidine biosynthesis, PRPP => histidine

M00033 - Ectoine biosynthesis, aspartate => ectoine

M00050 - Guanine ribonucleotide biosynthesis IMP => GDP,GTP

M00051 - Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP

M00061 - D-Glucuronate degradation

M00064 - ADP-L-glycero-D-manno-heptose biosynthesis

M00086 - beta-Oxidation, acyl-CoA synthesis

M00093 - Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE

M00096 - C5 isoprenoid biosynthesis, non-mevalonate pathway

M00115 - NAD biosynthesis, aspartate => NAD

M00122 - Cobalamin biosynthesis, cobinamide => cobalamin

M00127 - Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P

M00140 - C1-unit interconversion, prokaryotes

M00157 - F-type ATPase, prokaryotes and chloroplasts

M00159 - V-type ATPase, prokaryotes

M00167 - Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P

M00307 - Pyruvate oxidation, pyruvate => acetyl-CoA

M00432 - Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

M00525 - Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine

M00526 - Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine

M00527 - Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine

M00535 - Isoleucine biosynthesis, pyruvate => 2-oxobutanoate

M00552 - D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P

M00554 - Nucleotide sugar biosynthesis, galactose => UDP-galactose

M00565 - Trehalose biosynthesis, D-glucose 1P => trehalose

M00570 - Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine

M00579 - Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate

M00609 - Cysteine biosynthesis, methionine => cysteine

M00620 - Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate

M00627 - beta-Lactam resistance, Bla system

M00631 - D-Galacturonate degradation (bacteria)

M00632 - Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P

M00704 - Tetracycline resistance, efflux pump Tet38

M00705 - Multidrug resistance, efflux pump MepA

M00793 - dTDP-L-rhamnose biosynthesis

M00843 - L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4

M00844 - Arginine biosynthesis, ornithine => arginine

M00845 - Arginine biosynthesis, glutamate => acetylcitrulline => arginine

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Antibiotic resistance




Virulence factor class


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Virulence factor gene


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Secondary metabolite


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MATLAB species model file: msp_0049.mat