| Species: | Klebsiella michiganensis 2 |
|---|---|
| Genus: | Klebsiella |
| Family: | Enterobacteriaceae |
| Order: | Enterobacterales |
| Class: | Gammaproteobacteria |
| Phylum: | Proteobacteria |
| Gut outflow: | 1 |
|---|---|
| Disease Association: |
Colon adenoma (ES=0.326194) |
In the linked pathways:
red=enriched, blue=depleted
ko00010 - Glycolysis / Gluconeogenesis
ko00020 - Citrate cycle (TCA cycle)
ko00030 - Pentose phosphate pathway
ko00040 - Pentose and glucuronate interconversions
ko00051 - Fructose and mannose metabolism
ko00052 - Galactose metabolism
ko00053 - Ascorbate and aldarate metabolism
ko00061 - Fatty acid biosynthesis
ko00130 - Ubiquinone and other terpenoid-quinone biosynthesis
ko00240 - Pyrimidine metabolism
ko00250 - Alanine, aspartate and glutamate metabolism
ko00260 - Glycine, serine and threonine metabolism
ko00270 - Cysteine and methionine metabolism
ko00281 - Geraniol degradation
ko00290 - Valine, leucine and isoleucine biosynthesis
ko00300 - Lysine biosynthesis
ko00350 - Tyrosine metabolism
ko00360 - Phenylalanine metabolism
ko00400 - Phenylalanine, tyrosine and tryptophan biosynthesis
ko00410 - beta-Alanine metabolism
ko00450 - Selenocompound metabolism
ko00460 - Cyanoamino acid metabolism
ko00471 - D-Glutamine and D-glutamate metabolism
ko00473 - D-Alanine metabolism
ko00480 - Glutathione metabolism
ko00500 - Starch and sucrose metabolism
ko00520 - Amino sugar and nucleotide sugar metabolism
ko00521 - Streptomycin biosynthesis
ko00540 - Lipopolysaccharide biosynthesis
ko00550 - Peptidoglycan biosynthesis
ko00620 - Pyruvate metabolism
ko00630 - Glyoxylate and dicarboxylate metabolism
ko00640 - Propanoate metabolism
ko00660 - C5-Branched dibasic acid metabolism
ko00670 - One carbon pool by folate
ko00710 - Carbon fixation in photosynthetic organisms
ko00720 - Carbon fixation pathways in prokaryotes
ko00730 - Thiamine metabolism
ko00750 - Vitamin B6 metabolism
ko00760 - Nicotinate and nicotinamide metabolism
ko00770 - Pantothenate and CoA biosynthesis
ko00780 - Biotin metabolism
ko00785 - Lipoic acid metabolism
ko00903 - Limonene and pinene degradation
ko00910 - Nitrogen metabolism
ko00920 - Sulfur metabolism
ko00970 - Aminoacyl-tRNA biosynthesis
ko00983 - Drug metabolism - other enzymes
ko01053 - Biosynthesis of siderophore group nonribosomal peptides
ko01110 - Biosynthesis of secondary metabolites
ko02010 - ABC transporters
ko02030 - Bacterial chemotaxis
ko02060 - Phosphotransferase system (PTS)
ko03030 - DNA replication
ko03060 - Protein export
ko03070 - Bacterial secretion system
ko03410 - Base excision repair
ko03430 - Mismatch repair
ko03440 - Homologous recombination
M00002 - Glycolysis, core module involving three-carbon compounds
M00003 - Gluconeogenesis, oxaloacetate => fructose-6P
M00005 - PRPP biosynthesis, ribose 5P => PRPP
M00006 - Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
M00007 - Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
M00008 - Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
M00010 - Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00012 - Glyoxylate cycle
M00016 - Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00017 - Methionine biosynthesis, apartate => homoserine => methionine
M00018 - Threonine biosynthesis, aspartate => homoserine => threonine
M00019 - Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00020 - Serine biosynthesis, glycerate-3P => serine
M00021 - Cysteine biosynthesis, serine => cysteine
M00049 - Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
M00050 - Guanine ribonucleotide biosynthesis IMP => GDP,GTP
M00060 - Lipopolysaccharide biosynthesis, KDO2-lipid A
M00061 - D-Glucuronate degradation
M00063 - CMP-KDO biosynthesis
M00064 - ADP-L-glycero-D-manno-heptose biosynthesis
M00086 - beta-Oxidation, acyl-CoA synthesis
M00093 - Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
M00116 - Menaquinone biosynthesis, chorismate => menaquinol
M00117 - Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone
M00119 - Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00121 - Heme biosynthesis, glutamate => heme
M00124 - Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P
M00136 - GABA biosynthesis, prokaryotes, putrescine => GABA
M00144 - NADH
M00149 - Succinate dehydrogenase, prokaryotes
M00150 - Fumarate reductase, prokaryotes
M00153 - Cytochrome bd ubiquinol oxidase
M00157 - F-type ATPase, prokaryotes and chloroplasts
M00176 - Assimilatory sulfate reduction, sulfate => H2S
M00364 - C10-C20 isoprenoid biosynthesis, bacteria
M00365 - C10-C20 isoprenoid biosynthesis, archaea
M00417 - Cytochrome o ubiquinol oxidase
M00432 - Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
M00526 - Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527 - Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
M00533 - Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
M00535 - Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
M00537 - Xylene degradation, xylene => methylbenzoate
M00550 - Ascorbate degradation, ascorbate => D-xylulose-5P
M00552 - D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P
M00554 - Nucleotide sugar biosynthesis, galactose => UDP-galactose
M00565 - Trehalose biosynthesis, D-glucose 1P => trehalose
M00570 - Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
M00572 - Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
M00631 - D-Galacturonate degradation (bacteria)
M00632 - Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
M00642 - Multidrug resistance, efflux pump MexJK-OprM
M00696 - Multidrug resistance, efflux pump AcrEF-TolC
M00718 - Multidrug resistance, efflux pump MexAB-OprM
M00740 - Methylaspartate cycle
M00745 - Imipenem resistance, repression of porin OprD
M00761 - Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
M00793 - dTDP-L-rhamnose biosynthesis
M00843 - L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
M00844 - Arginine biosynthesis, ornithine => arginine
M00845 - Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00846 - Siroheme biosynthesis, glutamate => siroheme
Adherence
Adhesion
Biofilm
Cell motility
Cell surface and membrane proteins
Cell-to-cell spread
Cellular metabolism
Chaperone
Drug efflux system
Escape from the phagosome
Intracellular survival and replication
Invasion
Regulation of gene expression
Secretion
Stress
Virulence
Zinc uptake
16 kDa heat shock protein A (ID:SL1344_3776)
16 kDa heat shock protein B (ID:c4606)
3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (ID:SEN0882)
ATP-dependent helicase HrpA (ID:Z2313)
Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) (ID:Z0038)
Carbon starvation protein A (ID:SL1344_0588)
CFA/I fimbrial major subunit (ID:Z0360)
Chorismate synthase (EC 4.2.3.5) (ID:t0480)
Cobyrinic acid a,c-diamide synthetase (EC 6.3.5.11) (ID:SG2061)
Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) (ID:SL1344_0436)
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) (ID:Z4251)
Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1), subgroup 1 (ID:SL1344_0209)
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (ID:c1081)
Dipeptide ABC transporter, substrate-binding protein DppA (TC 3.A.1.5.2) @ Dipeptide chemoreceptor (ID:c4361)
DNA polymerase IV (EC 2.7.7.7) (ID:SL1344_0309)
DNA-binding transcriptional dual regulator SoxS (ID:STM14_5127)
DTDP-4-amino-4,6-dideoxygalactose transaminase (EC 2.6.1.59) (ID:c4711)
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (EC 5.2.1.8) (ID:STM3453)
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD (EC 5.2.1.8) (ID:STM474_3621)
Formate efflux transporter FocA (ID:SL1344_0911)
Galactose/methyl galactoside ABC transporter, ATP-binding protein MglA (EC 3.6.3.17) (ID:Z3404)
GMP synthase [glutamine-hydrolyzing], amidotransferase subunit (EC 6.3.5.2) / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit (EC 6.3.5.2) (ID:S2725)
GTP-binding and nucleic acid-binding protein YchF (ID:c1661)
Holliday junction ATP-dependent DNA helicase RuvB (EC 3.6.4.12) (ID:SL1344_1828)
Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I (ID:SEN2801)
Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain (ID:STM2511)
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (ID:SL1344_1747)
Lysine/cadaverine antiporter membrane protein CadB (ID:STM474_2663)
Manganese ABC transporter, periplasmic-binding protein SitA (ID:SL1344_2841)
Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) (ID:SL1344_3451)
Mg(2+) transport ATPase, P-type (EC 3.6.3.2) (ID:STM14_4536)
Multidrug efflux pump MdfA/Cmr (of MFS type), broad spectrum (ID:STM14_1016)
Murein peptide ABC transporter, substrate-binding protein (requires DppBCDF) (ID:c1803)
N,N'-diacetylchitobiose-specific 6-phospho-beta-glucosidase (EC 3.2.1.86) (ID:STM474_1321)
Na+/H+-dicarboxylate symporter (ID:Z4942)
NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) (ID:STM2323.S)
Outer membrane protein A precursor (ID:c1093)
Outer membrane usher protein FimD (ID:c5396)
Outer-membrane-phospholipid-binding lipoprotein MlaA (ID:S2559)
Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34) (ID:SL1344_0566)
Peptidyl-prolyl cis-trans isomerase PpiC (EC 5.2.1.8) (ID:SL1344_3870)
Periplasmic beta-glucosidase (EC 3.2.1.21) (ID:SL1344_2144)
Periplasmic chaperone and peptidyl-prolyl cis-trans isomerase of outer membrane proteins SurA (EC 5.2.1.8) (ID:SF0050)
Periplasmic chaperone of outer membrane proteins Skp @ Outer membrane protein H precursor (ID:SF2457T_4958)
Periplasmic thiol:disulfide interchange protein DsbA (ID:SFV_3641)
Phosphate transport system regulatory protein PhoU (ID:c4648)
Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (ID:STM14_5016)
PTS system, galactitol-specific IIC component (ID:b2092)
PTS system, N,N'-diacetylchitobiose-specific IIB component (EC 2.7.1.196) (ID:SL1344_1247)
Pyruvate formate-lyase activating enzyme (EC 1.97.1.4) (ID:STM474_0956)
Respiratory nitrate reductase alpha chain (EC 1.7.99.4) (ID:b1224)
RNA polymerase sigma factor RpoS (ID:SEN2763)
RNA polymerase-binding transcription factor DksA (ID:S0140)
SbmA protein (ID:c0482)
Signal transduction histidine-protein kinase BarA (EC 2.7.13.3) (ID:SL1344_2939)
Thioredoxin 2 (ID:Z3867)
TonB-dependent receptor; Outer membrane receptor for ferric enterobactin and colicins B, D (ID:STM14_0682)
Trk potassium uptake system protein TrkA (ID:Z4660)
Type 1 fimbriae regulatory protein FimB (ID:c5391)
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.191) (ID:STM0226)
UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (ID:SL1344_2057)
Uncharacterized protease YegQ (ID:SL1344_2112)
Uncharacterized protein YjaG (ID:SL1344_4108)
Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.33) (ID:S3902)
UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (ID:S1322)
UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (ID:SL1344_2075)
Zinc ABC transporter, substrate-binding protein ZnuA (ID:STM14_2300)
Non-ribosomal peptide synthetase (NRPS)
Type-I polyketide synthetase (PKS)
